Included in the museum is the fabulous "Bragg Collection" which is a vast collection of Mr. and Mrs. Clyde Bragg accumulated over a period of 26 years. Construction on the Bragg Collection layout started on March 5, 2005; the first trains on the layout were run on June 4, 2005, in conjunction with the Cotton Belt Depot centennial celebration. The Bragg Collection consists of about 200 locomotives and over 1,600 rail cars. Additionally, there is a vast collection of house, vehicles, airport, bridges and other miscellaneous pieces.

In addition to the Bragg Collection, there are three other model train layouts that were donated as well as a host of artifacts from by-gone years of the railroad industry. There also are many pictures, uniforms, hats, etc. that have been donated by former employees and friends of the depot. Many of these artifacts date into the late 1800s and encompass a large area of the Cotton Belt Depot Museum. The Museum accepts artifacts from donors as an out-right gift or on loan.

Visitors to the museum also are able to get a “hands-on” chance to run the controls for an elaborate model train system. The Cotton Belt Depot Museum also hosts tours from area schools as well as Scouts and various other groups such as travel clubs, churches and senior citizen groups. The volunteers from the Cotton Belt Rail Historical Society who staff the Cotton Belt Depot do their best to arrange their schedules to accommodate these groups.